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Glossary

A

Adhesion

Criticality: 2

The attraction between molecules of different substances.

Example:

Water climbing up a paper towel against gravity is an example of adhesion, as water molecules stick to the cellulose fibers.

Amino

Criticality: 2

A functional group (-NH2) consisting of a nitrogen atom bonded to two hydrogen atoms, which can act as a base by accepting a proton.

Example:

The amino group in an amino acid gives it basic properties, allowing it to accept H+ ions.

Amino acids

Criticality: 3

The monomeric building blocks of proteins, each containing an amino group, a carboxyl group, a hydrogen atom, and a unique R-group (side chain) attached to a central carbon atom.

Example:

There are 20 different common amino acids that can be combined in countless ways to form diverse proteins.

C

Carbohydrates

Criticality: 3

Macromolecules composed of carbon, hydrogen, and oxygen, primarily functioning as short-term energy storage and structural components.

Example:

Pasta provides your body with carbohydrates like starch, which are broken down into glucose for quick energy.

Carbonyl

Criticality: 2

A functional group (C=O) consisting of a carbon atom double-bonded to an oxygen atom, found in sugars.

Example:

Sugars like glucose and fructose contain a carbonyl group, which contributes to their reactivity.

Carboxyl

Criticality: 2

A functional group (-COOH) consisting of a carbon atom double-bonded to an oxygen atom and single-bonded to a hydroxyl group; it is acidic.

Example:

Amino acids contain a carboxyl group, which can donate a proton and act as an acid.

Cohesion

Criticality: 2

The attraction between molecules of the same substance, often due to hydrogen bonding.

Example:

Water droplets on a leaf demonstrate cohesion, as the water molecules stick together to form a spherical shape.

Covalent Bonds

Criticality: 2

Strong chemical bonds formed when two atoms share electrons, holding atoms together within a molecule.

Example:

The oxygen and hydrogen atoms within a single water molecule are held together by strong covalent bonds.

D

DNA

Criticality: 3

Deoxyribonucleic acid; a double-stranded nucleic acid that stores the genetic instructions for the development, functioning, growth, and reproduction of all known organisms.

Example:

Your unique genetic blueprint is encoded in the sequence of bases within your DNA.

Dehydration Synthesis

Criticality: 3

A chemical reaction that builds polymers by joining monomers, with the removal of a water molecule for each bond formed.

Example:

When your body builds muscle, amino acids are linked together via dehydration synthesis to form new protein strands.

Denaturing

Criticality: 3

The process by which a protein loses its specific three-dimensional shape and, consequently, its biological function, often due to changes in temperature, pH, or salinity.

Example:

Cooking an egg causes the proteins in the egg white to undergo denaturing, changing from clear liquid to solid white.

E

Evaporative Cooling

Criticality: 2

The process by which the evaporation of water from a surface removes heat, leading to a cooling effect.

Example:

When you sweat during exercise, the evaporative cooling of the sweat helps to lower your body temperature.

F

Functional Groups

Criticality: 3

Specific clusters of atoms within molecules that are responsible for the characteristic chemical reactions and properties of those molecules.

Example:

The presence of a hydroxyl (functional group) makes alcohols polar and able to form hydrogen bonds.

H

High Specific Heat

Criticality: 3

The amount of heat energy required to raise the temperature of a substance by a certain amount, which is high for water.

Example:

Oceans have a high specific heat, which helps moderate global temperatures and prevents drastic temperature swings.

Hydrogen Bonds

Criticality: 3

Weak intermolecular forces that form between a slightly positive hydrogen atom of one polar molecule and a slightly negative atom (like oxygen or nitrogen) of another polar molecule.

Example:

Hydrogen bonds are responsible for water's unique properties, like its ability to stick to itself and other surfaces.

Hydrolysis

Criticality: 3

A chemical reaction that breaks down polymers into monomers by adding a water molecule, which splits the bond.

Example:

During digestion, complex carbohydrates are broken down into simpler sugars through hydrolysis reactions.

Hydrophilic

Criticality: 2

Describes substances that are 'water-loving' and readily dissolve in or mix with water, typically due to their polarity.

Example:

Sugar is hydrophilic, which is why it easily dissolves when stirred into a glass of water.

Hydrophobic

Criticality: 2

Describes substances that are 'water-fearing' and do not dissolve in or mix with water, typically because they are nonpolar.

Example:

Oil is hydrophobic, which is why it separates into distinct layers when mixed with water.

Hydroxyl

Criticality: 2

A functional group (-OH) consisting of an oxygen atom bonded to a hydrogen atom, making molecules polar and capable of hydrogen bonding.

Example:

Alcohols and carbohydrates are rich in hydroxyl groups, making them soluble in water.

L

Lipids

Criticality: 3

A diverse group of hydrophobic macromolecules, including fats, oils, phospholipids, and steroids, primarily used for long-term energy storage, insulation, and cell membrane structure.

Example:

The cell membrane is primarily composed of lipids, specifically phospholipids, which create a barrier.

M

Macromolecules

Criticality: 3

Large, complex organic molecules essential for life, built from smaller repeating subunits.

Example:

Proteins, carbohydrates, lipids, and nucleic acids are the four major classes of macromolecules found in living organisms.

Monomers

Criticality: 3

Small, repeating molecular units that can be linked together to form larger polymers.

Example:

Amino acids are the monomers that link together to build a protein.

N

Nucleic Acids

Criticality: 3

Macromolecules that store and transmit genetic information, composed of nucleotide monomers.

Example:

DNA and RNA are the two main types of nucleic acids essential for heredity and protein synthesis.

Nucleotides

Criticality: 3

The monomeric building blocks of nucleic acids, each consisting of a five-carbon sugar, a phosphate group, and a nitrogenous base.

Example:

ATP, the energy currency of the cell, is a modified nucleotide.

P

Phosphate

Criticality: 2

A functional group (-PO4) consisting of a phosphorus atom bonded to four oxygen atoms, often found in nucleic acids and ATP, and carrying a negative charge.

Example:

The backbone of DNA is made of alternating sugar and phosphate groups.

Phospholipids

Criticality: 3

A type of lipid with a hydrophilic head (phosphate group) and two hydrophobic tails (fatty acids), forming the basic structure of cell membranes.

Example:

The cell membrane is a bilayer of phospholipids, with their hydrophilic heads facing the watery environments inside and outside the cell.

Polar molecule

Criticality: 3

A molecule with an unequal distribution of charge, resulting in a slightly positive end and a slightly negative end.

Example:

Water is a polar molecule because oxygen pulls electrons more strongly than hydrogen, creating distinct partial charges.

Polymers

Criticality: 3

Large molecules composed of many repeating monomer subunits linked together.

Example:

Starch is a polymer made up of many glucose monomers joined in a long chain.

Primary structure (protein)

Criticality: 2

The unique linear sequence of amino acids in a polypeptide chain, determined by genetic information.

Example:

The specific order of amino acids in a protein, like the sequence in insulin, defines its primary structure.

Proteins

Criticality: 3

Complex macromolecules made of amino acid monomers, performing a vast array of functions including catalyzing reactions, transport, structural support, and immune response.

Example:

Enzymes, which speed up chemical reactions in your body, are a type of protein.

Q

Quaternary structure (protein)

Criticality: 2

The overall protein structure that results from the aggregation of two or more separate polypeptide chains (subunits).

Example:

Hemoglobin, which carries oxygen in red blood cells, exhibits quaternary structure because it is made of four distinct polypeptide chains.

R

RNA

Criticality: 3

Ribonucleic acid; a single-stranded nucleic acid that plays various roles in gene expression, including carrying genetic information from DNA to ribosomes and participating in protein synthesis.

Example:

Messenger RNA (mRNA) carries the instructions from a gene in the nucleus to the ribosomes in the cytoplasm to build a protein.

S

Saturated Fats

Criticality: 2

Lipids characterized by fatty acid chains with only single bonds between carbon atoms, making them solid at room temperature.

Example:

Butter contains a high proportion of saturated fats, which is why it remains solid at room temperature.

Secondary structure (protein)

Criticality: 2

Local folded structures that form within a polypeptide due to hydrogen bonding between atoms of the polypeptide backbone, commonly forming alpha-helices or beta-sheets.

Example:

The spiral shape of an alpha-helix in a protein is an example of its secondary structure.

Sulfhydryl

Criticality: 2

A functional group (-SH) consisting of a sulfur atom bonded to a hydrogen atom, important in stabilizing protein structure through disulfide bridges.

Example:

The sulfhydryl group in the amino acid cysteine allows proteins to form disulfide bonds, crucial for their 3D shape.

Surface Tension

Criticality: 2

The property of a liquid's surface that allows it to resist an external force, due to the cohesive forces between its molecules.

Example:

A water strider can walk on water due to the high surface tension created by the hydrogen bonds at the water's surface.

T

Tertiary structure (protein)

Criticality: 3

The overall three-dimensional shape of a single polypeptide chain, resulting from interactions between the R-groups of the amino acids.

Example:

The complex globular shape of an enzyme, allowing it to bind to its specific substrate, is its tertiary structure.

U

Unsaturated Fats

Criticality: 2

Lipids characterized by fatty acid chains containing one or more double bonds between carbon atoms, causing kinks and making them liquid at room temperature.

Example:

Olive oil is rich in unsaturated fats, contributing to its liquid state at room temperature.