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Glossary

A

ATP

Criticality: 3

Adenosine triphosphate, the primary energy currency of the cell, used to power most cellular processes, including active transport.

Example:

Muscle contraction requires a constant supply of ATP to fuel the movement of protein filaments.

Active Transport

Criticality: 3

The movement of substances across a cell membrane against their concentration gradient, from an area of low concentration to an area of high concentration, requiring energy (ATP).

Example:

Nerve cells use the sodium-potassium pump for active transport to maintain ion gradients crucial for transmitting signals.

B

Bulk Transport

Criticality: 3

A type of active transport that moves large molecules or large quantities of smaller molecules into or out of the cell using vesicles.

Example:

Immune cells engulfing bacteria is an example of bulk transport, specifically phagocytosis.

C

Concentration Gradient

Criticality: 3

The difference in the concentration of a substance between two areas, driving passive transport from high to low concentration.

Example:

The movement of carbon dioxide out of your cells is driven by a concentration gradient where CO2 is higher inside the cell than outside.

E

Endocytosis

Criticality: 3

A form of bulk transport where the cell membrane engulfs substances from the extracellular fluid, forming a vesicle to bring them into the cell.

Example:

When a white blood cell 'eats' a pathogen, it's performing endocytosis to internalize the foreign material.

Exocytosis

Criticality: 3

A form of bulk transport where vesicles fuse with the cell membrane, releasing their contents from inside the cell to the extracellular environment.

Example:

Pancreatic cells release insulin into the bloodstream through exocytosis.

F

Facilitated Diffusion

Criticality: 3

The movement of polar molecules or ions across a cell membrane from high to low concentration with the assistance of specific transport proteins, but without energy expenditure.

Example:

Glucose enters red blood cells via facilitated diffusion, using a specific protein channel to cross the membrane quickly.

M

Membrane Transport

Criticality: 3

The process by which substances move across the cell membrane, essential for maintaining cell function and homeostasis.

Example:

Understanding membrane transport helps explain how cells absorb nutrients and expel waste products to survive.

O

Osmosis

Criticality: 3

The facilitated diffusion of water across a selectively permeable membrane from an area of higher water concentration (lower solute concentration) to an area of lower water concentration (higher solute concentration).

Example:

If you place a plant cell in pure water, osmosis will cause water to move into the cell, making it turgid.

P

Passive Transport

Criticality: 3

Movement of substances across a cell membrane that does not require cellular energy (ATP). It occurs down the concentration gradient.

Example:

When you smell perfume across a room, the scent molecules are spreading via passive transport from an area of high concentration to low.

Phagocytosis

Criticality: 2

A specific type of endocytosis, often called 'cellular eating,' where the cell engulfs large particles, whole cells, or debris by extending pseudopods.

Example:

A macrophage performing phagocytosis consumes bacterial cells as part of the immune response.

Pinocytosis

Criticality: 2

A type of endocytosis, known as 'cellular drinking,' where the cell takes in extracellular fluid containing dissolved solutes by forming small vesicles.

Example:

Cells lining capillaries use pinocytosis to absorb small molecules and fluid from the blood.

R

Receptor-Mediated Endocytosis

Criticality: 2

A highly specific type of endocytosis where specific molecules bind to receptors on the cell surface, triggering the formation of a coated vesicle to internalize the bound substances.

Example:

Cells take up cholesterol from the blood via receptor-mediated endocytosis, using specific LDL receptors.

S

Simple Diffusion

Criticality: 2

The direct movement of small, nonpolar molecules from an area of high concentration to an area of low concentration across the cell membrane, without the help of transport proteins.

Example:

Oxygen easily moves from the high concentration in your lungs into the lower concentration in your bloodstream through simple diffusion.

T

Transport Protein

Criticality: 3

A protein embedded in the cell membrane that facilitates the movement of specific substances across the membrane, either through facilitated diffusion or active transport.

Example:

Ion channels are a type of transport protein that allows specific ions to pass through the cell membrane.