Cell Communication and Cell Cycle
During signal transduction, what role does a second messenger like cyclic AMP (cAMP) play following hormonal stimulation?
It deactivates the receptor preventing any further signals from being received.
It acts as an enzyme directly catalyzing reactions that produce cellular responses.
It transports ions across the membrane to change membrane potential immediately.
It amplifies the signal received from outside and triggers further steps within the pathway.
What type of molecule typically binds to a receptor on the surface of a cell to initiate a signal transduction pathway?
Ribosome
Polymerase
Phospholipid
Ligand
In which metabolic pathway does oxygen act as the final electron acceptor?
Photosynthesis
Aerobic cellular respiration
Glycolysis
Anaerobic respiration
Which hypothetical drug's mechanism is most likely interfering with hormonal signaling in cells lacking second messengers?
Competitive antagonist that blocks adenylate cyclase coupled hormone receptors
Agonist mimics action natural hormone inducing stronger long-lasting effects
Allosteric modulator binds away from active site enhancing enzyme-substrate affinity
Non-competitive inhibitor reduces cholesterol synthesis affecting steroid hormone production
In a pedigree chart displaying a rare autosomal recessive disorder, what does it indicate if two unaffected parents have an affected child?
One parent is homozygous dominant, and the other is a carrier.
Both parents are heterozygous carriers of the disorder.
Both parents are unaffected due to incomplete penetrance.
The trait is not actually autosomal recessive but X-linked recessive.
What will be the expected impact of an aberrant version of the Smad protein that cannot be phosphorylated, but can still bind TGF-beta receptors in a cell?
The cell will not successfully transmit the TGF-beta signaling to the nucleus and induce gene expression changes.
Smad proteins will still form complexes with Smad anchoring proteins to mediate translocation to the nucleus at increased rates.
Smad proteins will cause localized downstream signaling overactivation to dominate the cellular response.
Smad proteins will experience no change in functionality due to redundant pathways that circumvent the need for their phosphorylation.
Which type of molecule is typically responsible for amplifying the signal in a signal transduction pathway?
Second messenger
Receptor protein
Structural protein
Transport protein

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What consequence might result from a defect in G-protein coupled receptor (GPCR) function where it remains active longer than normal after ligand binding?
Increased frequency random mutations genetic material caused chronic stimulation
Altered cellular responses such as prolonged fight-or-flight reaction due hormonal imbalance
Unresponsive cell behavior despite presence external stimuli because inability transmit further down line
Diminished ability detect changes environment leading reduced adaptation skills
When studying signal transductions using molecular data from phosphorylation cascades within different organisms’ cells, which inference regarding evolutionary relationships could you make?
Disparity in overall pathway layouts implies convergent evolution of unrelated lineages.
Absence of certain kinases indicates recent evolution of divergent species.
Similarity between phosphorylation components suggests common ancestry shared by organisms.
Homology among a few second messengers hints that large-scale horizontal transfer occurred.
How does a ligand-gated ion channel function in neuronal signal transduction after binding with its ligand?
It detaches from the membrane and transports ions through cytoplasmic vesicles.
It phosphorylates adjacent channels, increasing their permeability non-specifically.
It enters the nucleus and acts as a transcription factor for neuron-specific genes.
It changes shape allowing specific ions to flow across the membrane and alter membrane potential.