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Glossary

A

Acetylcholine

Criticality: 3

A neurotransmitter that enables muscle action, learning, and memory; its deterioration is linked to Alzheimer's disease.

Example:

When you decide to pick up a pen, acetylcholine is released to signal your muscles to contract.

Anti-anxiety drugs (Tranquilizers)

Criticality: 3

Medications used to control anxiety and agitation by depressing activity in the central nervous system.

Example:

Before a big presentation, some people might take an anti-anxiety drug to calm their nerves, but they must be aware of the risk of dependence.

Antidepressants

Criticality: 3

Medications primarily used to treat depression, anxiety disorders, OCD, and PTSD by increasing the availability of certain neurotransmitters like serotonin and norepinephrine in the brain.

Example:

After starting antidepressants, Sarah noticed a gradual improvement in her mood and energy levels over several weeks.

Antipsychotics

Criticality: 3

Medications primarily used to treat psychotic symptoms, such as those seen in schizophrenia, by decreasing dopamine levels in the brain.

Example:

A patient experiencing hallucinations might be prescribed antipsychotics to help reduce these perceptual disturbances.

B

Biological psychology

Criticality: 3

A field of psychology that examines how our biology, including our brains, neurotransmitters, and genetics, influences our behavior and mental processes.

Example:

A researcher studying how brain injuries affect personality is working within the field of biological psychology.

D

Deep-Brain Stimulation

Criticality: 1

A surgical procedure that involves implanting electrodes in specific brain areas to activate the frontal lobes and limbic system, sometimes used for severe depression or OCD.

Example:

In rare cases of extreme OCD, Deep-Brain Stimulation might be considered to help regulate brain circuits associated with the disorder.

Dependence

Criticality: 2

A state in which a person experiences withdrawal symptoms if they stop taking a drug, indicating a physical or psychological reliance.

Example:

Someone who experiences severe nausea and tremors when they try to stop drinking coffee might be experiencing caffeine dependence.

Dopamine

Criticality: 3

A neurotransmitter that influences movement, learning, attention, and emotion; an excess is linked to schizophrenia, while a deficit is linked to Parkinson's disease.

Example:

The reward pathway in the brain releases dopamine when you achieve a goal, making you feel pleasure and motivating you to repeat the action.

Double-blind procedure

Criticality: 3

An experimental procedure in which neither the participants nor the research staff know who has received the treatment and who has received a placebo, to prevent bias.

Example:

In a study testing a new pain reliever, a double-blind procedure would ensure that neither the patients nor the nurses administering the pills knew who was getting the real drug.

E

Electroconvulsive Therapy (ECT)

Criticality: 3

A biomedical therapy for severe depression where a brief electric current is sent through the brain of an anesthetized patient, inducing a seizure.

Example:

For severe, treatment-resistant depression, a doctor might recommend Electroconvulsive Therapy after other options have failed.

M

Mood stabilizers

Criticality: 2

Medications used to help even out the extreme mood swings characteristic of bipolar disorder, balancing periods of mania and depression.

Example:

Lithium is a common mood stabilizer prescribed to help individuals with bipolar disorder maintain a more consistent emotional state.

N

Neurogenesis

Criticality: 2

The process of generating new neurons in the brain, which is thought to be promoted by some antidepressant medications.

Example:

The slow onset of antidepressant effects is partly due to the gradual process of neurogenesis in the brain.

Norepinephrine

Criticality: 3

A neurotransmitter involved in alertness and arousal, as well as mood; undersupply can depress mood.

Example:

During a stressful situation, your body releases norepinephrine to increase your heart rate and sharpen your focus, preparing you for a 'fight or flight' response.

P

Prefrontal lobotomy

Criticality: 2

A historical and largely abandoned psychosurgical procedure that involved severing connections in the brain's frontal lobes, often resulting in severe side effects.

Example:

The prefrontal lobotomy was once used to calm agitated patients, but its devastating impact on personality and cognitive function led to its discontinuation.

Psychopharmacology

Criticality: 3

The study of how drugs affect the mind and behavior, particularly in the context of treating psychological disorders.

Example:

A psychiatrist prescribing an antidepressant is applying principles of psychopharmacology to help a patient's mood.

Psychosurgery

Criticality: 2

A highly invasive and rarely used biomedical procedure that involves removing or destroying parts of the brain to treat severe psychological disorders.

Example:

Due to its irreversible nature and high risks, psychosurgery is considered a last resort for mental health treatment.

R

Random assignment

Criticality: 3

A procedure in experiments where participants are assigned to either the experimental or control group by chance, minimizing pre-existing differences between the groups.

Example:

To ensure the drug trial was fair, researchers used random assignment to decide which participants received the actual medication and which received a placebo.

Random selection

Criticality: 2

A method of choosing participants from a population such that every member has an equal chance of being included in the study, aiming for a representative sample.

Example:

To survey student opinions, a school might use random selection by picking every tenth name from the student roster.

Repetitive Transcranial Magnetic Stimulation (rTMS)

Criticality: 2

A non-invasive procedure that uses magnetic energy pulses to stimulate or suppress brain activity, used for conditions like depression and ASD.

Example:

Unlike ECT, Repetitive Transcranial Magnetic Stimulation is a painless procedure that can activate specific brain regions.

S

SNRIs (Selective Norepinephrine Reuptake Inhibitors)

Criticality: 2

A class of antidepressants that work by blocking the reuptake of norepinephrine, thereby increasing its availability in the brain's synapses.

Example:

Some individuals with depression find that SNRIs are effective in boosting their energy and focus, in addition to improving mood.

SSRIs (Selective Serotonin Reuptake Inhibitors)

Criticality: 3

A class of antidepressants that work by blocking the reuptake of serotonin, thereby increasing its availability in the brain's synapses.

Example:

Prozac is a well-known SSRI that helps improve mood by allowing serotonin to remain in the synaptic cleft for longer.

Serotonin

Criticality: 3

A neurotransmitter that affects mood, hunger, sleep, and arousal; undersupply is linked to depression.

Example:

Many antidepressants work by increasing the availability of serotonin in the brain, helping to lift a person's mood.

T

Tardive dyskinesia

Criticality: 3

A potential side effect of long-term use of antipsychotic drugs, characterized by involuntary movements of the facial muscles, tongue, and limbs.

Example:

The patient developed tardive dyskinesia, causing uncontrollable grimacing and lip-smacking, after years of taking antipsychotic medication.

Tolerance

Criticality: 2

A state where a person needs increasingly larger doses of a drug to achieve the same effect, often seen with anti-anxiety medications.

Example:

After taking the same pain medication for months, John developed tolerance and found he needed a higher dose to relieve his discomfort.