Federalist leaders met to discuss grievances and propose amendments to the Constitution during the War of 1812.

Aaron Burr was accused of plotting to create an independent state in the West.

William Henry Harrison defeated Tecumseh's forces, increasing tensions between the US and Native Americans.

Andrew Jackson invaded Spanish Florida to deal with Seminole raids and runaway slaves.

A protective tariff designed to promote American manufacturing by increasing the cost of imported goods.

A major economic downturn caused by land speculation, declining agricultural prices, and bank failures.

Maine was admitted as a free state, Missouri as a slave state, and slavery was prohibited in the Louisiana Purchase territory north of the 36°30′ parallel.

A series of conflicts between the US and Native American tribes in the Old Northwest.

A treaty where Native Americans were often cheated out of their land.

A military conflict between the United States and Great Britain, stemming from a variety of causes, including violations of U.S. maritime rights.

Causes: Federalist opposition to the War of 1812. Effects: Damaged the Federalist Party's reputation, leading to its decline.

Causes: Desire for land and economic opportunity. Effects: Conflict with Native Americans, displacement of indigenous populations.

Causes: Desire for economic self-sufficiency. Effects: Promoted domestic manufacturing and internal improvements, but faced opposition over constitutionality and regional favoritism.

Causes: Land speculation, declining agricultural prices, and bank failures. Effects: Economic downturn, bank closures, job losses.

Causes: Missouri's application for statehood as a slave state. Effects: Temporarily resolved the issue of slavery, but heightened sectional tensions.

Causes: US expansion into Native American lands. Effects: Increased tensions, the Battle of Tippecanoe, and ultimately the weakening of Native American resistance in the Old Northwest.

Causes: Seminole raids on US settlements and refuge for runaway slaves. Effects: US invasion of Spanish Florida, demonstrating US power and leading to the eventual acquisition of Florida.

Causes: Desire to stabilize currency and provide credit. Effects: Led to the Panic of 1819.

Causes: To promote American manufacturing. Effects: Increased the cost of imported goods, leading to regional tensions.

Causes: The United States wanted to secure access to the port of New Orleans and expand its territory. Effects: Doubled the size of the United States, opened vast new lands for settlement and agriculture, and raised questions about the expansion of slavery.

Former VP accused of plotting to create an independent state in the West.

A Shawnee religious leader who called for a return to traditional ways and rejection of American goods.

A Shawnee military leader who organized a confederacy to resist American expansion.

A leading politician who proposed the American System to promote economic self-sufficiency.

US General who defeated Tecumseh's forces at the Battle of Tippecanoe.

US General who invaded Spanish Florida during the First Seminole War.

A founding father and first Secretary of the Treasury, killed by Aaron Burr in a duel.

Third president of the United States.

Fourth president of the United States.

Proposed the Tallmadge Amendment to limit slavery in Missouri.