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Henderson-Hasselbalch Equation

Emily Wilson

Emily Wilson

8 min read

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Study Guide Overview

This guide covers the Henderson-Hasselbalch equation for understanding and working with buffers. It explains the equation's components (pH, pKa, [A-], [HA]), its application in calculating buffer pH, and its use in titration problems. The guide also includes practice questions and exam tips.

Mastering Buffers: Your Ultimate Guide to the Henderson-Hasselbalch Equation

Hey AP Chem student! Let's dive into the Henderson-Hasselbalch equation, your secret weapon for tackling buffer problems. This guide will break it down, step-by-step, so you feel confident and ready for anything the exam throws at you. Let's get started!

Introduction to Buffers and the Henderson-Hasselbalch Equation

Buffers are crucial in chemistry and biology, and the Henderson-Hasselbalch equation is your go-to tool for understanding them. Remember, buffers resist changes in pH and consist of a weak acid and its conjugate base (or a weak base and its conjugate acid). Let's get cozy with this equation:

Henderson-Hasselbalch Equation

Breaking Down the Equation

  • pH: The measure of acidity, calculated as -log[H+]. Often, this is what you're solving for.
  • pKa: -log(Ka), which tells us about the acid's strength. Remember, a lower pKa means a stronger acid.
  • log([A-]/[HA]): This is the log of the ratio of the conjugate base [A-] to the weak acid [HA]. This ratio is key to understanding buffer behavior. 💡
Key Concept

Remember, the strongest buffer action occurs when [A-] = [HA], making the log term zero, and pH = pKa.

Two Forms of the Henderson-Hasselbalch Equation

Applying the Henderson-Hasselbalch Equation: Example Problems

Let's see how to use this equation in action. We'll ta...